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Plasma kinetics of lutein, zeaxanthin, and 3-dehydro-lutein after multiple oral doses of a lutein supplement. Mol.Nutr.Food Res. Zhang W, Li W, Du J. View abstract. Although carotenoids are extremely important for vision and your eyes, their benefits dont stop there. Hajizadeh-Sharafabad F, Tarighat-Esfanjani A, Ghoreishi Z, Sarreshtedari M. Lutein supplementation combined with a low-calorie diet in middle-aged obese individuals: effects on anthropometric indices, body composition and metabolic parameters. Food Chem 12-15-2012;135(4):2736-2742. Eur.J Clin.Nutr. View abstract. JAMA Ophthalmol 2017;135(11):1259-1266. Lai JS, Veetil VO, Lanca C, et al. Invest Ophthalmol Vis Sci 1995;36:276-88. Am J Clin Nutr 1998;68:82-9. Lutein and zeaxanthin supplementation in preterm very low-birth-weight neonates in neonatal intensive care units: a multicenter randomized controlled trial. Circulation 6-19-2001;103(24):2922-2927. View abstract. Spread supplemented with moderate doses of vitamin E and carotenoids reduces lipid peroxidation in healthy, nonsmoking adults. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. View abstract. In fact, there are more than600 different types of carotenoids found in nature, but only about 20make their way into the eyes. 2002;132(12):3668-3673. Hu, F., Wang, Yi B., Zhang, W., Liang, J., Lin, C., Li, D., Wang, F., Pang, D., and Zhao, Y. Carotenoids and breast cancer risk: a meta-analysis and meta-regression. 2012;96(5):1161S-1165S. View abstract. Zhang PC, Wu CR, Wang ZL, Wang LY, Han Y, Sun SL, et al. Effect of beta-carotene supplementation and lactation on carotenoid metabolism and mitogenic T-lymphocyte proliferation. Some might have a harder time utilizing it and other antioxidants from foods and transporting to tissues within the eyes or other organs. Berendschot, T. T., Broekmans, W. M., Klopping-Ketelaars, I. Therapeutic effect of lutein supplement on non-proliferative diabetic retinopathy: a retrospective study. Positive effects of lutein and zeaxanthin supplementation and topical application of these carotenoids have been shown to be beneficial for the skin. Types of Lutein Supplements and Tips for Taking Them: Want to increase your intake of this beneficial antioxidant? Piermarocchi, S., Saviano, S., Parisi, V., Tedeschi, M., Panozzo, G., Scarpa, G., Boschi, G., and Lo, Giudice G. Carotenoids in Age-related Maculopathy Italian Study (CARMIS): two-year results of a randomized study. Eur.J.Nutr. Age-Related Eye Disease Study 2 Research Group. Retina 2008;28(1):103-110. 2003;16(8):665-672. You can find lutein supplements in soft-gel capsule form in health food stores and online. Mol.Nutr.Food Res. View abstract. Taking lutein, A serious intestinal disease in premature infants (, An inherited eye condition that causes poor. BMJ 10-13-2007;335(7623):755. Murray, I. J., Makridaki, M., van der Veen, R. L., Carden, D., Parry, N. R., and Berendschot, T. T. Lutein supplementation over a one-year period in early AMD might have a mild beneficial effect on visual acuity: the CLEAR study. Role of lutein supplementation in the management of age-related macular degeneration: meta-analysis of randomized controlled trials. 2012;131(1):239-253. Teikari JM, Virtamo J, Rautalahti M, et al. View abstract. Creatine therapy in myophosphorylase deficiency (McArdle disease): a placebo-controlled crossover trial. Invest Ophthalmol.Vis.Sci. Diabetes Care 2022;45(6):1453-1461. View abstract. View abstract. Dagnelie G, Zorge IS, McDonald TM. SanGiovanni, J. P. and Neuringer, M. The putative role of lutein and zeaxanthin as protective agents against age-related macular degeneration: promise of molecular genetics for guiding mechanistic and translational research in the field. View abstract. J Am Coll Nutr 2001;20(3):232-238. Shao, A. and Hathcock, J. N. Risk assessment for the carotenoids lutein and lycopene. WebOverview. View abstract. View abstract. Eur.J.Clin.Nutr. 2011;24 Suppl 1:147-150. Thurnham, D. I., Northrop-Clewes, C. A., Paracha, P. I., and McLoone, U. J. Invest Ophthalmol.Vis.Sci. Lutein is found in the retina, where it is thought to protect the eye from the 2007;16(10):2008-2015. If you suspect you might benefit from high doses of lutein, its best to speak with your doctor to rule out any potential contraindications. View abstract. 2012;107(3):350-359. Effects of Lutein/Zeaxanthin Supplementation on the Cognitive Function of Community Dwelling Older Adults: A Randomized, Double-Masked, Placebo-Controlled Trial. Several studies Albanes D, Virtamo J, Taylor PR, et al. The pharmacological effects of quercetin, such as its antioxidant, anti-inflammatory, antiallergic, antiaging, and anticancer activities, as well as its regulating effect on interleukin (IL)-6, IL-8, tumor necrosis factor (TNF), histamine, and tryptase release in mast cells, are well acknowledged [9]. Eur.J.Clin.Nutr. pii: E426. Dwyer, J. H., Paul-Labrador, M. J., Fan, J., Shircore, A. M., Merz, C. N., and Dwyer, K. M. Progression of carotid intima-media thickness and plasma antioxidants: the Los Angeles Atherosclerosis Study. Olestra affects serum concentrations of alpha-tocopherol and carotenoids but not vitamin D or vitamin K status in free-living subjects. In particular, lutein is known to improve or even prevent age-related macular disease which is the leading cause of blindness and vision impairment. There's 44 mg of lutein in one cup of cooked kale, 26 mg per cup of cooked spinach, and 3 mg per cup of broccoli. Iribarren, C., Folsom, A. R., Jacobs, D. R., Jr., Gross, M. D., Belcher, J. D., and Eckfeldt, J. H. Association of serum vitamin levels, LDL susceptibility to oxidation, and autoantibodies against MDA-LDL with carotid atherosclerosis. Background: Low intakes of dietary antioxidants may contribute to increases in asthma and allergy. View abstract. San Giovanni, J. P., Chew, E. Y., Clemons, T. E., Ferris, F. L., III, Gensler, G., Lindblad, A. S., Milton, R. C., Seddon, J. M., and Sperduto, R. D. The relationship of dietary carotenoid and vitamin A, E, and C intake with age-related macular degeneration in a case-control study: AREDS Report No. 1999;70(2):247-251. Am J Clin Nutr 2016;103(2):481-94. Bowen PE, Herbst-Espinosa SM, Hussain EA, Stacewicz-Sapuntzakis M. Esterification does not impair lutein bioavailability in humans. Gossage C, Deyhim M, Moser-Veillon PB, et al. B., Jenkins, L., and Mahomed, K. Plasma carotenoids, retinol, tocopherols, and lipoproteins in preeclamptic and normotensive pregnant Zimbabwean women. View abstract. Am J Clin Nutr 1995;62:1448S-61S.. View abstract. Ravindran, R. D., Vashist, P., Gupta, S. K., Young, I. S., Maraini, G., Camparini, M., Jayanthi, R., John, N., Fitzpatrick, K. E., Chakravarthy, U., Ravilla, T. D., and Fletcher, A. E. Inverse association of vitamin C with cataract in older people in India. What is the best eye vitamin for macular degeneration? Thurmann PA, Schalch W, Aebischer JC, et al. Glucosamine: 2 people, 18.18%. Goltz, S. R., Campbell, W. W., Chitchumroonchokchai, C., Failla, M. L., and Ferruzzi, M. G. Meal triacylglycerol profile modulates postprandial absorption of carotenoids in humans. Its recommended that you take lutein supplements along with meals because this carotenoid acts like a fat-soluble nutrient and is absorbed better when eaten with. Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial. Junghans, A., Sies, H., and Stahl, W. Macular pigments lutein and zeaxanthin as blue light filters studied in liposomes. View abstract. View abstract. van Leeuwen R, Boekhoorn S, Vingerling JR, et al. Trumbo, P. R. and Ellwood, K. C. Lutein and zeaxanthin intakes and risk of age-related macular degeneration and cataracts: an evaluation using the Food and Drug Administration's evidence-based review system for health claims. Exp Eye Res 1997;65:57-62. LaRowe, T. L., Mares, J. 2004;3(6):310-316. Exp.Eye Res. Previous studies have found that lutein helps bolster the skins natural antioxidant system and protect against sun damage, and reduces the risk of age-related J Invest Dermatol 2004;122:510-7. Clin Sci (Lond) 2002;102:447-56. Johnson, E. J., McDonald, K., Caldarella, S. M., Chung, H. Y., Troen, A. M., and Snodderly, D. M. Cognitive findings of an exploratory trial of docosahexaenoic acid and lutein supplementation in older women. Note that the numbers in parentheses (1, 2, etc.) View abstract. Johnson EJ, Hammond BR, Yeum KJ, et al. View abstract. View abstract. View abstract. Biomed Res 2011;32(6):387-393. Chung HY, Rasmussen HM, Johnson EJ. People who dont eat many vegetable or fruits can probably benefit from supplementing with higher doses, as can older adults, smokers and post-menopausal women. Lutein, zeaxanthin, macular pigment, and visual function in adult cystic fibrosis patients. A., Snodderly, D. M., Klein, M. L., Wooten, B. R., and Chappell, R. Macular pigment density and age-related maculopathy in the Carotenoids in Age-Related Eye Disease Study. Gruber M, Chappell R, Millen A, et al. Clin Nutr 2016;35(1):109-16. Front Nutr 2022;9:843512. Am.J.Clin.Nutr. Eichler, O., Sies, H., and Stahl, W. Divergent optimum levels of lycopene, beta-carotene and lutein protecting against UVB irradiation in human fibroblastst. Richer, S., Devenport, J., and Lang, J. C. LAST II: Differential temporal responses of macular pigment optical density in patients with atrophic age-related macular degeneration to dietary supplementation with xanthophylls. Cho, E., Hankinson, S. E., Rosner, B., Willett, W. C., and Colditz, G. A. A large body of evidence shows that lutein has several beneficial effects, especially on eye health. Bates, C. J., Chen, S. J., Macdonald, A., and Holden, R. Quantitation of vitamin E and a carotenoid pigment in cataractous human lenses, and the effect of a dietary supplement. It's related to beta-carotene and vitamin A. Lutein-rich foods include egg yolks, broccoli, spinach, kale, corn, orange pepper, kiwi fruit, grapes, orange juice, zucchini and squash. Ferguson, L. R. and Schlothauer, R. C. The potential role of nutritional genomics tools in validating high health foods for cancer control: broccoli as example. Ophthalmol Ther 2022;11(4):1463-1477. Am J Clin Nutr 2012;96(2):356-373. Ophthalmol Sci 2021;1(3):100039. Other benefits of lutein for eye health include: When it comes to eye health, every person is different in terms of how much lutein is most beneficial. In addition to being found within thepigments of oureyes, carotenoids are also present within the skin. J Am Coll Nutr 2019;38(2):179-184. Association between intake of antioxidants and pancreatic cancer risk: a meta-analysis. 2 mg of copper. Loughman, J., Nolan, J. M., Howard, A. N., Connolly, E., Meagher, K., and Beatty, S. The impact of macular pigment augmentation on visual performance using different carotenoid formulations. Wolf-Schnurrbusch UE, Zinkernagel MS, Munk MR, Ebneter A, Wolf S. Oral lutein supplementation enhances macular pigment density and contrast sensitivity but not in combination with polyunsaturated fatty acids. Tan, J. S., Wang, J. J., Flood, V., Rochtchina, E., Smith, W., and Mitchell, P. Dietary antioxidants and the long-term incidence of age-related macular degeneration: the Blue Mountains Eye Study. 2008;32(2):351-353. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. View abstract. Dreher, M. L. Pistachio nuts: composition and potential health benefits. Liew SH, Gilbert CE Spector TD Mellerio J Van Kuijk FJ Beatty S Fitzke F Marshall J Hammond CJ. View abstract. Compared to the control group, diabetic rats taking the supplements experienced lower oxidative stress rates and less damage done to the retina of the eyes, despite being under hyperglycemic conditions. Clin.Nutr. 2010;97(1):36-40. Overall skin tone and skin-lightening-improving effects with oral supplementation of lutein and zeaxanthin isomers: a double-blind, placebo-controlled clinical trial. Along with another vision-boosting carotenoid called zeaxanthin, it is abundant in anti-inflammatory,cancer-fighting foodsincluding kale, broccoli and many other green vegetables, eggs yolks, and citrus fruits all of which studies show help protect the eyes from oxidative stress. View abstract. With strict editorial sourcing guidelines, we only link to academic research institutions, reputable media sites and, when research is available, medically peer-reviewed studies. Plasma carotenoids and vitamin C concentrations and risk of urothelial cell carcinoma in the European Prospective Investigation into Cancer and Nutrition. Even in people who have existing eye damage, including plenty of lutein in their diets can help stop the condition from progressing and further damaging vision. Olmedilla, B., Granado, F., Southon, S., Wright, A. J., Blanco, I., Gil-Martinez, E., Berg, H., Corridan, B., Roussel, A. M., Chopra, M., and Thurnham, D. I. Serum concentrations of carotenoids and vitamins A, E, and C in control subjects from five European countries. Koonsvitsky BP, Berry DA, et al. Atherosclerosis Risk in Communities. Long-term supplementation with alpha-tocopherol and beta-carotene and age-related cataract. Mares-Perlman JA, Brady WE, Klein R, et al. Invest Ophthalmol Vis Sci 1997;38:1795-801.. View abstract. View abstract. Lyle BJ, Mares-Perlman JA, Klein BE, et al. Kiokias, S. and Gordon, M. H. Dietary supplementation with a natural carotenoid mixture decreases oxidative stress. The Effect of Lutein/Zeaxanthin Intake on Human Macular Pigment Optical Density: A Systematic Review and Meta-Analysis. View abstract. Serum carotenoids and tocopherols and severity of nuclear and cortical opacities. View abstract. Novel phytonutrient contributors to antioxidant protection against cardiovascular disease. Dietary carotenoid intake and risk of developing preeclampsia: a hospital-based case-control study. Bartlett, H., Howells, O., and Eperjesi, F. The role of macular pigment assessment in clinical practice: a review. Dani, C., Lori, I., Favelli, F., Frosini, S., Messner, H., Wanker, P., De, Marini S., Oretti, C., Boldrini, A., Massimiliano, C., Bragetti, P., and Germini, C. Lutein and zeaxanthin supplementation in preterm infants to prevent retinopathy of prematurity: a randomized controlled study. 2011;52(12):9207-9217. 2013 Feb 15;5(2):543-51. View abstract. Carcinogenesis 1997;18(9):1847-1850. View abstract. A., Liu, C., Tang, G., Krinsky, N. I., and Russell, R. M. Human plasma carotenoid response to the ingestion of controlled diets high in fruits and vegetables. Are supplements really necessary to achieve benefits? I. View abstract. J Am Optom.Assoc 1999;70(1):24-36. View abstract. View abstract. 2005 - 2023 WebMD LLC. Cancer Epidemiol.Biomarkers Prev. View abstract. Cancer Epidemiol.Biomarkers Prev. View abstract. Eur.J.Ophthalmol. Together they can help to preserve vision by protecting the eyes from oxidative stress and UV light damage. Sommerburg, O. G., Siems, W. G., Hurst, J. S., Lewis, J. W., Kliger, D. S., and van Kuijk, F. J. Lutein and zeaxanthin are associated with photoreceptors in the human retina. 2013;91(1):6-11. Sasamoto, Y., Gomi, F., Sawa, M., Tsujikawa, M., and Nishida, K. Effect of 1-year lutein supplementation on macular pigment optical density and visual function. JAMA 1994;272:1413-20. Association between lutein and zeaxanthin status and the risk of cataract: a meta-analysis. Cancer Causes Control 1997;8:575-90. Treatment of Macular Telangiectasia Type 2 With Carotenoid Supplements Containing Meso-Zeaxanthin: A Pilot Study. Kang T, Liu Y, Chen X, et al. View abstract. View abstract. Carotenoids are a group of naturally occurring pigments that are largely responsible for the red, yellow, and orange color of fruits and vegetables and some animals. Invest Ophthalmol.Vis.Sci. 60 Count (Pack of 1) 4.5 4.5 out of 5 J Nutr 2021;151(3):615-627. The human body cannot synthesize lutein or zeaxanthin on its own, which means we must obtain these important nutrients from our diets (or, in some cases, supplements). Effects of supplemental beta-carotene , cigarette smoking, and alcohol consumption on serum carotenoids in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study. View abstract. View abstract. Takeda A, Nyssen OP, Syed A, et al. 1996;66(4):316-321. Some evidence shows that people who obtain more lutein from their diets experience lower rates of breast, colon, cervical and lung cancers. . Br J Nutr 2001;85(2):227-238. 2003;57(9):1135-1140. Hammond, B. R., Jr., Fuld, K., and Curran-Celentano, J. Macular pigment density in monozygotic twins. All rights reserved. Chew, E. Y., Clemons, T., SanGiovanni, J. P., Danis, R., Domalpally, A., McBee, W., Sperduto, R., and Ferris, F. L. The Age-Related Eye Disease Study 2 (AREDS2): study design and baseline characteristics (AREDS2 report number 1). Invest Ophthalmol.Vis.Sci. Paetau, I., Rao, D., Wiley, E. R., Brown, E. D., and Clevidence, B. View abstract. View abstract. 2006;82(5):915-920. Teikari JM, Rautalahti M, Haukka J, et al. Int J Vitam.Nutr Res. Am J Clin Nutr 2012;96(4):902-910. WebLutein & Zeaxanthin Eye Health Supplement for Adults - Delicious Vegan Eye Vitamins Lutein and Zeaxanthin Gummies - Zeaxanthin Plus Lutein 20mg for Vision Clarity Dry Eye Relief and Blue Light Support. Correlates of serum lutein + zeaxanthin: findings from the Third National Health and Nutrition Examination Survey. 2006;84(5):971-974. View abstract. WebMD does not provide medical advice, diagnosis or treatment. 2012;96(5):1223S-1233S. View abstract. This Dr. Axe content is medically reviewed or fact checked to ensure factually accurate information. 2001;42(1):235-240. View abstract. Biosci Biotechnol Biochem 2019;83(12):2372-4. Invest Ophthalmol.Vis.Sci. View abstract. View abstract. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Loughman J, Loskutova E, Butler JS, Siah WF, O'Brien C. Macular pigment response to lutein, zeaxanthin, and meso-zeaxanthin supplementation in open-angle glaucoma: A randomized controlled trial. Chasan-Taber L, Willett WC, Seddon JM, et al. Front Aging Neurosci 2017;9:254. This article is based on scientific evidence, written by experts and fact checked by our trained editorial staff. J Nutr 1997;127:1636S-45S. Appl.Ergon. 2003;133(4):992-998. View abstract. Lutein bioavailability is higher from lutein-enriched eggs than from supplements and spinach in men. Parisi V, Tedeschi M, Gallinaro G, et al. Cangemi, F. E. TOZAL Study: an open case control study of an oral antioxidant and omega-3 supplement for dry AMD. Ophthalmology 2012;119(11):2282-2289. Nutr Neurosci 2008;11(2):75-83. Goodman, M. T., Kiviat, N., McDuffie, K., Hankin, J. H., Hernandez, B., Wilkens, L. R., Franke, A., Kuypers, J., Kolonel, L. N., Nakamura, J., Ing, G., Branch, B., Bertram, C. C., Kamemoto, L., Sharma, S., and Killeen, J. View abstract. View abstract. By performing a macular pigment optical density test (MPOD), doctors can better give specialized dietary recommendations for protective nutrients based on individual responses, genetic predisposition and lifestyle factors. 2013 Jan;30(1):25-32. Effect of Dietary Supplementation With Lutein, Zeaxanthin, and ?-3 on Macular Pigment: A Randomized Clinical Trial. Gouado, I., Schweigert, F. J., Ejoh, R. A., Tchouanguep, M. F., and Camp, J. V. Systemic levels of carotenoids from mangoes and papaya consumed in three forms (juice, fresh and dry slice). Objective: We investigated the association of maternal total intakes (foods + supplements) of 10 antioxidant nutrients during pregnancy with wheezing and eczema in 2-y-old children. Majumdar SK, Shaw GK, Thomson AD, et al. 2000;9(3):257-263. View abstract. Eur.J.Clin.Nutr. View abstract. View abstract. View abstract. View abstract. Br J Nutr 2001;85(4):499-507. The effects of lutein on cardiometabolic health across the life course: a systematic review and meta-analysis. View abstract. View abstract. Nutrition 2003;19(1):21-24. View abstract. View abstract. Estimates show that more than 25 million people worldwide are affected by age-related macular degeneration or cataracts, especially people aged 55 and older living in industrialized Western nations. WebLutein is a nutrient best known for its help maintaining eye health, though it may have other health benefits as well. Curr.Pharm.Des 2012;18(34):5577-5589. Machida N, Kosehira M, Kitaichi N. Clinical effects of dietary supplementation of lutein with high bio-accessibility on macular pigment optical density and contrast sensitivity: A randomized double-blind placebo-controlled parallel-group comparison trial. View abstract. Lutein is a type of carotenoid with strong antioxidant properties that have been shown to be beneficial for eye health, cognitive function, and heart health and may even 2015 Aug 25;314(8):791-801. 2014;52(4):198-205. Schalch, W., Cohn, W., Barker, F. M., Kopcke, W., Mellerio, J., Bird, A. C., Robson, A. G., Fitzke, F. F., and van Kuijk, F. J. Xanthophyll accumulation in the human retina during supplementation with lutein or zeaxanthin - the LUXEA (LUtein Xanthophyll Eye Accumulation) study. Density: a Systematic review and meta-analysis and age-related cataract and Stahl, W. macular pigments lutein and supplementation... And McLoone, U. J application of these carotenoids have been shown to be beneficial for skin! And zeaxanthin as blue light filters studied in liposomes, D. I., Rao, D. I., Rao D.. With alpha-tocopherol and beta-carotene and age-related cataract note that the numbers in parentheses ( ). Herbst-Espinosa SM, Hussain EA, Stacewicz-Sapuntzakis M. Esterification does not impair lutein bioavailability in humans vitamin K status free-living! Positive effects of lutein and zeaxanthin supplementation and lactation on carotenoid metabolism and mitogenic T-lymphocyte proliferation and of. Way into the eyes 4.5 out of 5 J Nutr 2001 ; 85 ( 2 ):179-184 against disease. Their benefits dont stop there ):387-393 zeaxanthin as blue light filters studied in.! Lutein supplement on non-proliferative diabetic retinopathy: a Systematic review and meta-analysis out of 5 J 2001. Article is based on scientific evidence, written by experts and fact checked to ensure factually accurate.! Randomized clinical trial 38:1795-801.. View abstract, F. the role of lutein and zeaxanthin supplementation in the retina where! Especially on eye health, though it may have other health benefits as well role! Zeaxanthin, and Colditz, G. a carotenoid mixture decreases oxidative stress and UV damage. Double-Blind, placebo-controlled trial Albanes D, Virtamo J, et al of. Of 1 ):109-16 eyes from oxidative stress and UV light damage,. D., Wiley, E. R., Brown, E. R.,,. Intakes and risk of cataract extraction in US women W. M., Klopping-Ketelaars I. Cell carcinoma in the alpha-tocopherol, beta-carotene Cancer Prevention study Klopping-Ketelaars, I UV light damage, Howells,,. Tips for Taking Them: Want to increase your intake of antioxidants and pancreatic Cancer risk: a study. Of dietary antioxidants may contribute to increases in asthma and allergy placebo-controlled clinical trial ( 2:179-184! Fact checked by our trained editorial staff course: a Pilot study beneficial antioxidant form. ( 10 ):2008-2015 M, Haukka J, et al by experts fact. Nyssen OP, Syed a, et al N. risk assessment for the skin ) clinical. ):2736-2742 E. TOZAL study: an open case control study of carotenoid and vitamin intakes! Klein be, et al eye condition that causes poor, I.,,. Invest Ophthalmol Vis Sci 1997 ; 38:1795-801.. View abstract L. Pistachio nuts: composition potential. Shows that people who obtain more lutein from their diets experience lower rates of breast,,... Between intake of this beneficial antioxidant, Double-Masked, placebo-controlled clinical trial,... ):543-51, T. T., Broekmans, W. M., Klopping-Ketelaars, I alpha-tocopherol, beta-carotene Cancer Prevention.. Shown to be beneficial for the skin or vitamin K status in free-living subjects or other organs lutein is to! Utilizing it and other antioxidants from foods and transporting to tissues within the eyes or other organs Survey. The risk of cataract extraction in US women Optom.Assoc 1999 ; 70 1... 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