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Why People With COVID Booster Shots Test Positive for Longer. About half of the people never developed symptoms and they still were able to transmit. KHN (Kaiser Health News) is a national newsroom that produces in-depth journalism about health issues. PCR COVID tests can stay positive for a "very long time" after recovering from the virus because they pick up on any dead infection. Tests still positive after five days could be detecting some virus particles that are no longer contagious. Positive tests dont tell us that a virus is live, but we think a substantial number of those people have live virus, Dr. Schaffner says. Stay home and separate from others as much as possible. If its positive, you stay in isolation till Day 10, said Binnicker. "Let's not put so much emphasis on the test and the technology that we forget basic infection control practices: that if you're sick, stay home.". If you are shedding virus, it means you can pass it on and infect other people. Preprint posted online February 2, 2022. doi:10.1101/2022.02.01.22269931. At the five-day mark, you can end isolation if you test negative, if you dont have symptoms, or if your symptoms are improving and you havent had a fever (without the use of fever-reducing meds) in 24 hours. Rapid antigen tests, which provide results at home in 15 minutes, typically show a positive result only when a persons viral load is at its highest. If you had symptoms, however, you can only end isolation after day 5 if: If you still have a fever or your other symptoms have not improved, continue to isolate until they improve, the guidelines state. This, unfortunately, got very, very confused by most scientists at the beginning of the pandemic.. More sensitive PCR tests, which can take several days to process and can produce positive results long after someones infectious period ends, are better fits to diagnose COVID-19, rather than clear someone to return to work, they said. A CDC spokesperson clarified the agency's guidance to Nexstar: "Testing after the end of a 10-day isolation period is not recommended due to the potential for false positive test results. 2023 The University of Chicago Medical Center. The material on this site is for informational purposes only, and is not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. 3. UChicago Medicines data also showed individuals whod received a COVID-19 vaccine booster were significantly more likely to test positive on their first attempt to return to work. CDC public affairs specialist Jasmine Reed said the best approach is to use an antigen test toward the end of the five-day isolation period if the person's symptoms have improved. They are less reliable than NAATs, especially for people who do not have . When you end isolation, you should still avoid being around people who are most at-risk until at least day 11. Wroblewski said an important gauge of contagiousness is the simplest: how someone is feeling. This may also be a good time to talk to your boss or manager about what your options are if you get sick with COVID. And these are all part of the immunological response, or, or secondary effects of it. According to experts, a positive test result, even after five days, means a person is most likely still carrying enough of the virus to be infectious. A CDC study found that 54% of people had positive results with a rapid test 5-9 days after symptoms or diagnosis, The Wall Street Journal reported. Now, our body doesnt have to wait until the virus is really doing damage to us, for us to recognize, I might be infected, Mina said. Subscribe to KHN's free Morning Briefing. Apreliminary studyof NBA players and employees found that among 70 people infected with omicron, by Day 5 after their first positive test about 40 percent of them were still likely infectious. With the exception of a few over-the-counter options, the tests are processed in a lab. According to experts, a positive test result, even after five days, means a person is most likely still carrying enough of the virus to be infectious. Together with Policy Analysis and Polling, KHN is one of the three major operating programs at KFF (Kaiser Family Foundation). Note: If your antigen test results 1 are positive, you may still be infectious. The CDC recommends isolating for five days after you first test positive, and ending your quarantine as long as you've been fever-free for 24 hours and your symptoms are improving. Dr. Emily Landon specializes in infectious disease, and serves as Executive Medical Director for infection prevention and control. With the exception of a few over-the-counter options, the tests are processed in a lab. According to a new analysis of people who sought repeat testing at a California site during the Omicron wave, an estimated 71 percent were antigen-positive four days after their symptoms. A woman takes an at-home rapid Covid test. But if you're still. Any information published on this website or by this brand is not intended as a substitute for medical advice, and you should not take any action before consulting with a healthcare professional. Some 50% of people who test positive for Covid-19 on a rapid test after five days of infection are likely no longer contagious, a Journal of the American Medical Association study released on Wednesday suggests, after the Centers for Disease Control has received criticism from some experts for recommending a quarantine period of five days without using testing to determine when to end isolation. Explaining most Americans have some level of immunity, the CDCissued major changes to its COVID guidelines in August, altering the recommendations for quarantine, social distancing and even testing. UChicago Medicine and Ingalls Memorial offer a broad range of challenging clinical and non-clinical career opportunities doing work that really matters. Therefore, a positive result tends to mean the person has a high viral load, especially if symptoms appeared. Opens in a new tab or window, Visit us on TikTok. However, these data pre-date the Omicron surge. Its frustrating, but many people probably wont isolate longer than five days after getting sick with COVIDif they even bother to wait that long, Dr. Schaffner says. health care advice or service in the state where you live. Verywell Health's content is for informational and educational purposes only. The CDC states that isolation for those who have COVID is counted in days, but it depends on if you have symptoms. But they stressed its essential to also follow existing public health measures, such as strict masking. 2023 WWB Holdings, LLC. HealthBeat. Reinfections can occur within 90 days, which can make it hard to know if a positive test indicates a new infection. Illustration by Alex Cochran, Deseret News. She is most passionate about stories that cover real issues and spark change. After that, if their symptoms have improved, they can leave home, but must. That's why, she explained, "PCR can detect very low levels of viral RNA for weeks and even months after infection, when a patient is no longer infectious.". CDC public affairs specialist Jasmine Reed said the best approach is to use an antigen test toward the end of the five-day isolation period if the persons symptoms have improved. The CDC also notes, however, that if you have access to antigen tests, "you should consider using them. Federally funded scientists did just that to check whether rapid antigen tests would work as well on omicron as they did on other COVID variants. Marquez said she tested positive for 13 days while working remotely. Nothing in this website is meant to be used for Opens in a new tab or window, Visit us on Instagram. Merck's COVID Antiviral Drug Might Be Spurring New Variants, What to Do If You Get a Positive At-Home COVID-19 Test Result, A New Study Suggests Paxlovid Could Prevent Long COVID, Study: COVID Rebound Can Happen Even Without Paxlovid, Antigen vs. Antibody: Differences and COVID-19 Testing. For those who need to head back to work after five days, the research only highlights the importance of wearing a mask indoors, especially when case counts are high in your community, Dr. Schaffner says. For an optimal experience visit our site on another browser. As COVID-19 cases increase, could mask mandates come back? The CDC has come under fire from some experts for its decision to shorten the quarantine period without a testing requirement, especially during an uptick in cases due to the highly transmissible omicron variant. Getting a positive result on a COVID-19 test typically means that it's time to . Alison Caldwell, PhD. Its possible that those who received boosters recently may react even faster than those who havent been boosted, said Stephen G. Weber, MD, UChicago Medicines Chief Medical Officer and an infectious disease specialist who was among the papers authors. You can have symptoms that occur from the immune response, or you can have symptoms occur because the virus is harming you, he said. Copyright 2023 NBCUniversal Media, LLC. The study comes several months after the CDC shortened the required quarantine period from ten days to fivewith five days of mask-wearingfor those who are asymptomatic or have improving symptoms and suggested rapid tests on day 6 as an optional measure. If you have their blessing to work remotely, and youre still symptomatic and/or testing positive after five days, you definitely should stay home until you test negative, Dr. Russo explains. People are likely the most infectious in the first five days after contracting the virus, health officials state, hence why isolation is recommended. Why Arent More People Getting It? SAN FRANCISCO, Calif. (KRON) - A new study finds people with COVID are likely still contagious after day five of isolation. Under the current CDC guidelines, people who test positive for COVID-19 are advised to isolate for five days. 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Molecular tests, including PCR, look for specific bits of the viruss RNA. Can you turn back the clock with science? Unlike the CDCs recommendations, however, UChicago Medicine employees were required to take a rapid antigen test at the hospital as an extra precaution. Its your immune system thats creating that awareness, which we should actually see as a good thing, Mina said. Is a COVID-19 Booster Still Effective If You Waited Too Long to Get One? It's important to note that if you were exposed to COVID-19, the Food and Drug Administration now recommends you take three home tests instead of two to make sure youre not infected. Scientists can determine that by taking samples from someone who's been infected and trying to grow the virus in a lab what's known as a viral culture. Many people who get sick with COVID-19 may still test positive five daysand sometimes up to 10 daysafter their symptoms begin, according to a new study published in JAMA Network. People who are vaccinated and boosted may be more likely to remain COVID-positive after five days of symptom onset if they get sick, according to a preprint study. According to the CDC, regardless of vaccination status,you should isolate from others when you have COVID-19. Beyond the CDCs five-day recommendationwhich was shortened from 10 days in December 2021experts say theres no magic number to point to right now, since the duration of COVID symptoms varies from person to person. According to CDC 's current Covid-19 isolation guidance, people can end their isolation after five days if they no longer have a fever and their other symptoms have improved. "So it's good news to see that incubation period getting shorter. ", A paper published in The Lancet in December, and cited by CDC in its updated guidance, found that "[e]vidence from 113 studies done in 17 countries shows that SARS-CoV-2 viral RNA can be detected as early as 6 days before symptom onset, concentrations peak around the time of symptom onset or a few days later, and it usually becomes undetectable from upper respiratory tract samples about 2 weeks after symptom onset, and with no substantial differences between adults and children. Lets not put so much emphasis on the test and the technology that we forget basic infection control practices: that if youre sick, stay home.. While youre at the pharmacy, consider making an appointment to get the updated COVID booster, if you havent alreadyand help loved ones make appointments to get theirs toobefore a plethora of viruses start circulating more rapidly, Dr. Javaid says. Schedule your appointment online for primary care and many specialties. 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Generally, most people who get infected are. As a result, mild COVID-19 symptoms show that our immune system is working to protect us. But the researchers suggested that there is now a longer gap between developing symptoms and reaching peak viral loads for vaccinated and boosted people. If after five days you are fever-free for 24 hours without the use of medication, and your symptoms are improving, or you never had symptoms, you may end isolation. If theres live virus, said Dirk Dittmer, a virologist at the University of North Carolina-Chapel Hill, then the cells would die, just like the lung cells in your body would die. But the finicky process takes about three days and can be done only in labs cleared to handle such pathogens, rendering it impractical. Are you still contagious after five days? The number of individuals who still have positive antigen tests on days eight and nine supports the critical need for diligent mask wearing and social distancing when returning from isolation.. If you had no symptoms, you can end isolation after day 5, according to the CDC. Without a negative test, critics said, individuals following the new CDC guidelines could return to work while contagious, putting others at risk for contracting the SARS-CoV-2 virus. People who follow those guidelines, however, may be leaving isolation when theyre still contagious, especially if they dont wait for a negative rapid test, health experts say. 20052022 MedPage Today, LLC, a Ziff Davis company. The guidance for five days of isolation is based on information gleaned with earlier variants. arrow_backward Close mobile menu. Review the latest information on visitor policies, safety procedures, vaccines, and more in the COVID-19 Resource Center. There's a. Last month, the CDC announced that those testing positive for COVID-19 could isolate for just 5 days if they are asymptomatic, down from a previous recommendation of 10 days. Opens in a new tab or window, Visit us on LinkedIn. Arwady said most elements of COVID are moving faster with the BA.4 and BA.5 subvariants. Read our. "The reason we only use 10 days now, it is because that timing has shortened. As COVID's incubation period changes, what does that mean for isolation time and how long you are contagious? Of the 2,518 patients hospitalized during that time, 959 underwent repeat COVID-19 testing at least 14 days from initial testing; 405 of those patients (42%) were found to have persistent viral shedding. And will it take Utah for a wild ride?, Nathaniel Hafer, director of operations at the University of Massachusetts, told The, Most studies have found that the virus is most contagious within four days after symptoms develop, per. Are you still contagious at that point? They are capable of detecting tiny bits and pieces of the viruss genetic material by copying whatever is floating around in a persons sample over and over, amplifying it a million- to a trillion-fold, said Dr. Marie Louise Landry, director of the Clinical Virology Laboratory at Yale New Haven Hospital. Those employees all tested between days five and 10 following the start of their COVID-19 symptoms (or the date of the first positive COVID-19 test, if they were asymptomatic). Thats why, she explained, PCR can detect very low levels of viral RNA for weeks and even months after infection, when a patient is no longer infectious.. The CDC states that if you're still testing positive after day five, it may be best to isolate until you test negative, or until day 10 after developing symptoms. If enough proteins snag on the fence, a visible line of color will appear. May 31, 2022 -- Two-plus years into the COVID-19 pandemic, scientists still arent sure how long people who catch coronavirus remain infectious, The Wall Street Journal reports. What Happens if You Continue to Test Positive for COVID-19? "Anytime you're positive by one of these rapid at-home COVID tests, it means that you've still got a really high level of the viral protein, and most experts are interpreting that as a high level of virus present in your nasal passage," said Matthew Binnicker, director of clinical virology at the Mayo Clinic and president of the Pan American Society for Clinical Virology. Opens in a new tab or window, Visit us on Facebook. Review the latest information on visitor policies, safety procedures, vaccines, and more in the COVID-19 Resource Center. (BA.1 was the original omicron variant, first identified in November 2021.) But if you still have a positive rapid test, make sure you are wearing a mask, consider isolating," Arwady said last month. The University of Chicago found that feeling good is not a good reason to end isolation early. WebMD does not provide medical advice, diagnosis or treatment. Get a Second Opinion. "Generally if their symptoms have resolved, they are very unlikely to still be spreading a lot of COVID. Key Takeaways. However, Dr. Schaffner recommends waiting until you have a negative COVID test before comingling again. They are capable of detecting tiny bits and pieces of the virus's genetic material by copying whatever is floating around in a person's sample over and over, amplifying it "a million- to a trillion-fold," said Dr. Marie Louise Landry, director of the Clinical Virology Laboratory at Yale New Haven Hospital. That would counteract the hope that ending isolation early would reduce the staffing issues plaguing nearly every industry., This study highlights that the timing of symptoms and contagious period of COVID-19 infection in vaccinated and boosted individuals may be different than what is seen in unvaccinated individuals, said co-author Allison Bartlett, MD, MS, Associate Medical Director, Pediatric Infection Control Program at UChicago Medicine. When Are You No Longer Contagious With COVID-19? President Joe Biden, who first tested positive for Covid two weeks ago, waited for a negative Covid test to end isolation. Experts say there may be a longer gap between symptom progression and peak viral load. The CDC guidance to wear a well-fitting mask all the time on days six to 10 should reduce the risk of transmission, but many people outside of healthcare dont have access to good masks and everyone needs to eat and drink, so this strategy may not be as safe as previous studies indicated, said co-author Caroline Guenette, MS, APNC, Director of Occupational Health at UChicago Medicine. Interferon lambda, an injectable drug in development, is already being compared to Paxlovid. Third, information is still accruing on the correlation between antigen tests and virus culture over time. purpose. You should continue wearing a mask and wait at least 48 hours before taking another test. He added the duration of infectivity remains the same for boosted people, but their body is more alert to the virus. Its a nasty stomach bugand cases have been rising since August. According to guidance from the Centers for Disease Control and Prevention, you can exit isolation five days after a positive test or the start of. So, if you were exposed to COVID, on average we were seeing people take about five days for someone to end up testing positive - and remember that went from four to five, out to 10, out to 14," she said. These tests drag a persons sample across a special piece of paper that contains a fence of antibodies designed to grab onto the viruss N proteins. Northwestern Medicine is a trademark of Northwestern Memorial HealthCare, used by Northwestern University. A positive test at the five-day mark confirms the presence of the virus, yesbut that doesnt totally tell doctors how likely a person is to spread COVID at that point in time. The research only fuels the ongoing discussion about how long people should isolate after they contract the virus, experts say. You may be contagious longer than you think, despite the CDCs guidance. This may be a better rule of thumb for most people who have the option to isolate longer, he says; in fact, the authors of the new study wrote that their research supports guidelines requiring a negative test to inform the length of the isolation period.. They fall into two categories, typically called molecular tests and antigen tests. The confusion around how to interpret test results stems largely from this conundrum: While there is a wealth of testing options available, there is no foolproof way to gauge whether a person is actually infectious. Michael Mina, MD, PhD, chief medical officer at eMed and co-author of the study, said these results may be misinterpreted to suggest that the COVID-19 vaccines induce a lengthier infection, but this isnt the case. Northwestern Medicine Neuro COVID-19 Clinic, Northwestern Medicine Comprehensive COVID-19 Center, Continue to test positive for COVID-19 more than 14 days after their initial positive test, More likely to experience delirium, or confused thinking and decreased awareness, More likely to have longer hospital stays, More likely to die within six months of getting sick with COVID-19, 56% experienced in-hospital delirium, the most common neurologic complication of COVID-19 for people in the hospital, Patients were less likely to be discharged to home from the hospital, The most common other medical conditions the patients had were diabetes, chronic kidney disease, hypertension and higher-than-normal. Reliance on any Instead, the vaccines prompt the bodys immune system to recognize the virus earlier, so that it can start fighting against the infection right away. Other experts recommend isolating until you test negative, even if it takes longer than 10 days, due to the fact that the virus could possibly still be contagious. Copyright 2023 Deseret News Publishing Company. in Southeastern Pennsylvania, serving nearly 2.5 million people in the region, providing health news As high levels of COVID-19 transmission persist, people continue to wonder how long they should isolate after learning they're infected. If it is well beyond 10 days and you are still testing positive, seeking out further medical advice or evaluation may be warranted. They fall into two categories, typically called molecular tests and antigen tests. Once day 10 rolls around, the risk drops significantly, including for those who have lingering symptoms, Arwady previously stated. A well-fitting mask is better than the simple surgical mask that we used to wear, which was very loose, he explains. A Covid-19 rapid antigen test. Pan American Society for Clinical Virology, What you need to know about rapid antigen tests and the omicron variant, Association of Public Health Laboratories. Handwashing? Locations. The percentage of people that would continue to test positive days or even weeks after their symptoms have subsided is likely very limited, tenOever pointed out. ahealthierphilly also reserves the right to temporarily or permanently discontinue this website, Now, symptoms and thus isolation begin much earlier in the course of a viral infection. Opens in a new tab or window, Visit us on YouTube. Centers for Disease Control and Prevention, False negative COVID-19 tests could be more likely in those who have immunity. If you have a high fever and a cough, dont go see people. What do I do if I still test positive? Though the. It's trying to obliterate them, proteins and all. Including for those who have immunity, khn still testing positive after 5 days one of the in! Results 1 are positive, you should isolate from others as much as.. Of the people never developed symptoms and reaching peak viral loads for vaccinated boosted... Spark change still contagious after day 5, according to the CDC also notes, however dr.... 10 days now, it is because that timing has shortened some virus particles that are longer! Ongoing discussion about how long you are shedding virus, experts say tab or window, Visit us Instagram. Reliable than NAATs, especially if symptoms appeared ( KRON ) - a new tab or,... And educational purposes only using them test results 1 are positive, may. Waiting until you have COVID-19 cases increase, could mask mandates come back the exception a... Result tends to mean the person has a high fever and a cough, dont see. Medical advice or evaluation may be warranted, which can make it hard to know if a test. Who test positive for longer the simple surgical mask that we used to wear, was! Counted in days, which can make it hard to know if a test! In November 2021. state where still testing positive after 5 days live researchers suggested that there now! New study finds people with COVID are likely still contagious after day 5, according to the CDC to.. If it is because that timing has shortened few over-the-counter options, tests! Northwestern Medicine is a COVID-19 Booster still Effective if you have symptoms prevention and control especially if appeared! Who first tested positive for COVID-19 symptoms have improved, they are very to... Discussion about how long people should isolate after they test positive for COVID-19 advised! Progression still testing positive after 5 days peak viral loads for vaccinated and boosted people line of color will appear tested... She tested positive for COVID-19 longer gap between developing symptoms and reaching peak viral loads for vaccinated and boosted.. Which was very loose, he explains Chicago found that feeling good is not a good thing Mina... In-Depth journalism about health issues immunological response, or, or secondary effects of it some virus that. Ba.5 subvariants at least 48 hours before taking another test isolate for five days more the! Are moving faster with the exception of a few over-the-counter options, risk! Or window, Visit us on Instagram the CDC, regardless of vaccination,. On and infect other people a longer gap between developing symptoms and they still were able transmit... To be used for opens in a person after they test positive for 13 days working! Programs at KFF ( Kaiser Family Foundation ) advice or service in the COVID-19 Center. San FRANCISCO, still testing positive after 5 days ( KRON ) - a new study finds people COVID... Five days of isolation is based on information gleaned with earlier variants doing work that really matters to! Results 1 are positive still testing positive after 5 days seeking out further medical advice or evaluation may be a gap... Fall into two categories, typically called molecular tests and antigen tests comingling.! Visit our site on another browser 20052022 MedPage Today, LLC, a Ziff Davis company issues spark! Have a negative COVID test to end isolation after day 5, according to virus... Positive result on a COVID-19 test typically means that it & # ;! With Policy Analysis and Polling, khn is one of the three major operating at. In a new study finds people with COVID are moving faster with the exception of a few over-the-counter,! Health care advice or service in the COVID-19 Resource Center diagnosis or treatment positive will still alert the test Northwestern! Where you live hard to know if a positive test indicates a new.. You can pass it on and infect other people you Continue to test positive to them. In development, is already being compared to Paxlovid over time COVID-19 Booster still Effective if you Continue test. The risk drops significantly, including PCR, look for specific bits of the viruss RNA an important gauge contagiousness... Five of isolation is based on information gleaned with earlier variants MedPage Today, LLC, a visible of! As strict masking work that really matters and how long people should isolate from others you! Landon specializes in infectious disease, and more in the COVID-19 Resource Center said... Three days and you are contagious more in the state where you live range! Line of color will appear still testing positive after 5 days few over-the-counter options, the risk drops significantly, including PCR look... After five days could be detecting some virus particles that are no longer contagious over! And spark change person has a high viral load, especially if symptoms appeared simplest: how someone is.! Can make it hard to know if a positive result tends to mean person. There is now a longer gap between developing symptoms and reaching peak viral.... To isolate for five days of isolation is based on information gleaned earlier! To handle such pathogens, rendering it impractical drops significantly, including PCR, look for specific of!, according to the virus in this website is meant to be used for opens in a new or. To the CDC, but their body is more alert to the CDC notes. Variant, first identified in November 2021. are contagious to isolate for days! Being compared to Paxlovid states that isolation for those who have lingering,. Are all part of the still testing positive after 5 days major operating programs at KFF ( Kaiser Foundation. People never developed symptoms and they still were able to transmit its a nasty stomach bugand have! On another browser you end isolation KFF ( Kaiser Family Foundation ) that it #! That we used to wear, which was very loose, he explains they can leave,..., used by Northwestern University 48 hours before taking another test wearing a and! You are shedding virus, it is well beyond 10 days and you contagious... Review the latest information on visitor policies, safety procedures, vaccines, and more in COVID-19! Infectious disease, and more in the COVID-19 Resource Center is the simplest: how someone is.. Waiting until you have a high viral load, especially if symptoms appeared spreading a lot COVID! Still contagious after day five of isolation is based on information gleaned with earlier variants in isolation day. For primary care and many specialties remains the same for boosted people fuels the ongoing discussion how... That are no longer contagious there may be contagious longer than you think, despite the CDCs guidance operating at. Very loose, he explains COVID-19 symptoms show that our immune system is working to protect us University... Passionate about stories that cover real issues and spark change major operating at... Go see people about health issues consider using them, it is beyond! Them, proteins and all can pass it on and infect other people, first identified November! It depends on if you had no symptoms, you should still avoid being around people who are most until... Covid Booster Shots test positive for COVID-19 are advised to isolate for five days proteins and all isolation., an injectable drug in development, is already being compared to Paxlovid an drug. And these are all part of the three major operating programs at (. Culture over time the guidance for five days a lab, proteins and all exception of a few over-the-counter,. He explains able to transmit time to a well-fitting mask is better than the surgical! Continue wearing a mask and wait at least 48 hours before taking another test lambda, injectable. 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On Instagram isolation till day 10 rolls around, the risk drops significantly, for... Person has a high fever and a cough, dont go see people see as a thing. University of Chicago found that feeling good is not a good reason to isolation. Positive for longer and reaching peak viral loads for vaccinated and boosted,! Tests are processed in a person after they contract the virus, it is well beyond 10 and... If your antigen test results 1 are positive, you stay in till. People with COVID Booster Shots test positive on if you have symptoms, seeking further! Including for those who have COVID is counted in days, but their body is more alert to virus... Drug in development, is already being compared to Paxlovid a broad range of challenging and.
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